Insider purchase

1. 2033-11-18 HPK Hollis Michael L. (director) bought $208k of stock
2. 2026-11-06 MDGL BAKER BROS. ADVISORS LP; Baker Bros. Advisors (GP) LLC; BAKER FELIX; BAKER JULIAN; 667, L.P.; Baker Brothers Life Sciences LP (director) bought $23.1M of stock
3. 2026-11-06 KMI KINDER RICHARD D (director) bought $15.0M of stock
4. 2026-11-06 ANVS Hoffman Michael B (director) bought $5.0M of stock
5. 2026-11-06 MDGL BAKER BROS. ADVISORS LP; Baker Bros. Advisors (GP) LLC; BAKER FELIX; BAKER JULIAN; 667, L.P.; Baker Brothers Life Sciences LP (director) bought $5.3M of stock
6. 2026-11-06 CVS Shah Prem S (officer) bought $2.0M of stock
7. 2026-11-06 MDGL BAKER BROS. ADVISORS LP; Baker Bros. Advisors (GP) LLC; BAKER FELIX; BAKER JULIAN; 667, L.P.; Baker Brothers Life Sciences LP (director) bought $793k of stock
8. 2026-11-05 COUR Pale Fire Capital SE; Pale Fire Capital SICAV a.s.; Pale Fire Capital investicni spolecnost a.s.; Senkypl Dusan; Barta Jan (ten_percent_owner) bought $11.7M of stock
9. 2026-11-05 KOD BAKER BROS. ADVISORS LP; 667, L.P.; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP; BAKER FELIX; BAKER JULIAN (director) bought $8.1M of stock
10. 2026-11-05 GLXY Novogratz Michael; Galaxy Group Investments LLC (director) bought $6.7M of stock
11. 2026-11-05 GLXY Novogratz Michael; Galaxy Group Investments LLC (director) bought $3.2M of stock
12. 2026-11-05 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $915k of stock
13. 2026-11-05 ETRA GORDON CARL L (director) bought $915k of stock
14. 2026-11-05 TTMI Ali Wajid (director) bought $632k of stock
15. 2026-11-05 KOD BAKER BROS. ADVISORS LP; 667, L.P.; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP; BAKER FELIX; BAKER JULIAN (director) bought $463k of stock
16. 2026-11-05 MXE Saba Capital Management, L.P. (ten_percent_owner) bought $500k of stock
17. 2026-11-05 KYN Baker James C (director) bought $331k of stock
18. 2026-11-05 JOF Saba Capital Management, L.P. (ten_percent_owner) bought $299k of stock
19. 2026-11-05 TRNS IRICK JAIME A (director) bought $230k of stock
20. 2026-11-05 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $226k of stock
21. 2026-11-05 ETRA GORDON CARL L (director) bought $226k of stock
22. 2026-11-05 KMT Chowbey Sanjay (director) bought $165k of stock
23. 2026-11-05 MTUS RICE RONALD A (director) bought $166k of stock
24. 2026-11-05 MTDR Calvert Christopher P (officer) bought $105k of stock
25. 2026-11-05 ECF Saba Capital Management, L.P. (ten_percent_owner) bought $88k of stock
26. 2026-11-05 GFS MOORTHY GANESH (director) bought $94k of stock
27. 2026-11-05 GRX Saba Capital Management, L.P. (ten_percent_owner) bought $93k of stock
28. 2026-11-05 KYN Little Harrison James (officer) bought $52k of stock
29. 2026-11-04 LYEL ARCH Venture Partners IX, LLC; ARCH Venture Fund IX, L.P.; ARCH Venture Partners IX, L.P.; ARCH Venture Fund IX Overage, L.P.; ARCH Venture Partners IX Overage, L.P. (ten_percent_owner) bought $25.0M of stock
30. 2026-11-04 LYEL ARCH Venture Fund XIII, L.P.; ARCH Venture Partners XIII, L.P.; ARCH Venture Partners XIII, LLC; CRANDELL KEITH; GILLIS STEVEN; NELSEN ROBERT; Burow Kristina; BERNS PAUL L; BYBEE CLINTON (ten_percent_owner) bought $25.0M of stock
31. 2026-11-04 KOD BAKER BROS. ADVISORS LP; 667, L.P.; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP; BAKER FELIX; BAKER JULIAN (director) bought $15.0M of stock
32. 2026-11-04 COUR Pale Fire Capital SE; Pale Fire Capital SICAV a.s.; Pale Fire Capital investicni spolecnost a.s.; Senkypl Dusan; Barta Jan (ten_percent_owner) bought $10.4M of stock
33. 2026-11-04 MDGL BAKER BROS. ADVISORS LP; Baker Bros. Advisors (GP) LLC; BAKER FELIX; BAKER JULIAN; 667, L.P.; Baker Brothers Life Sciences LP (director) bought $3.7M of stock
34. 2026-11-04 LBTYA Rodriguez Enrique (officer) bought $2.0M of stock
35. 2026-11-04 MDGL BAKER BROS. ADVISORS LP; Baker Bros. Advisors (GP) LLC; BAKER FELIX; BAKER JULIAN; 667, L.P.; Baker Brothers Life Sciences LP (director) bought $2.1M of stock
36. 2026-11-04 PAM Mindlin Damian Miguel (officer) bought $1.3M of stock
37. 2026-11-04 BXMT Johnson Timothy Steven (director) bought $1.0M of stock
38. 2026-11-04 LBTYA FRIES MICHAEL T (director) bought $1.0M of stock
39. 2026-11-04 KOD BAKER BROS. ADVISORS LP; 667, L.P.; Baker Bros. Advisors (GP) LLC; Baker Brothers Life Sciences LP; BAKER FELIX; BAKER JULIAN (director) bought $861k of stock
40. 2026-11-04 LSCC Tamer Ford (director) bought $585k of stock
41. 2026-11-04 CLX Breber Pierre R (director) bought $400k of stock
42. 2026-11-04 LSCC Tamer Ford (director) bought $295k of stock
43. 2026-11-04 FLOC Fairbanks Jonathan B. (director) bought $293k of stock
44. 2026-11-04 MXE Saba Capital Management, L.P. (ten_percent_owner) bought $314k of stock
45. 2026-11-04 ETRA GORDON CARL L (director) bought $289k of stock
46. 2026-11-04 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $289k of stock
47. 2026-11-04 PAM Zuberbuhler Adolfo Fernando (officer) bought $207k of stock
48. 2026-11-04 SYY Ondrof Thomas Gerard (director) bought $192k of stock
49. 2026-11-04 LKQ GOVE SUE (director) bought $201k of stock
50. 2026-11-04 DGICA DONEGAL MUTUAL INSURANCE CO (ten_percent_owner) bought $142k of stock
51. 2026-11-04 ETRA GORDON CARL L (director) bought $141k of stock
52. 2026-11-04 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $141k of stock
53. 2026-11-04 LSCC Tamer Ford (director) bought $124k of stock
54. 2026-11-04 BXMT NASSAU HENRY N (director) bought $114k of stock
55. 2026-11-04 RRBI Price Teddy Ray (director) bought $95k of stock
56. 2026-11-04 PMN Williams Eugene (director) bought $91k of stock
57. 2026-11-04 ETRA GORDON CARL L (director) bought $72k of stock
58. 2026-11-04 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $72k of stock
59. 2026-11-03 KNOP Seglem Trygve (director) bought $43.5M of stock
60. 2026-11-03 CRBG NIPPON LIFE INSURANCE CO (ten_percent_owner) bought $12.6M of stock
61. 2026-11-03 DOLE Pale Fire Capital SE; Pale Fire Capital SICAV a.s.; Pale Fire Capital investicni spolecnost a.s.; Senkypl Dusan; Barta Jan (ten_percent_owner) bought $9.8M of stock
62. 2026-11-03 COUR Pale Fire Capital SE; Pale Fire Capital SICAV a.s.; Pale Fire Capital investicni spolecnost a.s.; Senkypl Dusan; Barta Jan (ten_percent_owner) bought $9.4M of stock
63. 2026-11-03 BRK-B BERKSHIRE HATHAWAY INC; BUFFETT WARREN E (ten_percent_owner) bought $3.4M of stock
64. 2026-11-03 LRN Haggart Dylan G.; Fivespan Partners, LP; Fivespan Partners GP, LLC (director) bought $2.4M of stock
65. 2026-11-03 PAM Mindlin Damian Miguel (officer) bought $1.3M of stock
66. 2026-11-03 FBRT Byrne Richard J (director) bought $998k of stock
67. 2026-11-03 ETRA GORDON CARL L (director) bought $767k of stock
68. 2026-11-03 ETRA GORDON CARL L (director) bought $777k of stock
69. 2026-11-03 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $767k of stock
70. 2026-11-03 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $777k of stock
71. 2026-11-03 BKR RICE JOHN G (director) bought $531k of stock
72. 2026-11-03 SPXC Deck Brian A (director) bought $493k of stock
73. 2026-11-03 LRN Haggart Dylan G.; Fivespan Partners, LP; Fivespan Partners GP, LLC (director) bought $370k of stock
74. 2026-11-03 LRN Shepherd Brian A. (director) bought $372k of stock
75. 2026-11-03 LRN Shepherd Brian A. (director) bought $378k of stock
76. 2026-11-03 LBRT Gusek Ron (director) bought $377k of stock
77. 2026-11-03 MXE Saba Capital Management, L.P. (ten_percent_owner) bought $284k of stock
78. 2026-11-03 CRBG NIPPON LIFE INSURANCE CO (ten_percent_owner) bought $279k of stock
79. 2026-11-03 JBLU Mittal Nik (director) bought $223k of stock
80. 2026-11-03 CRH Talbot Siobhan (director) bought $189k of stock
81. 2026-11-03 ETRA GORDON CARL L (director) bought $191k of stock
82. 2026-11-03 ETRA GORDON CARL L (director) bought $192k of stock
83. 2026-11-03 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $191k of stock
84. 2026-11-03 ETRA ORBIMED ADVISORS LLC; OrbiMed Capital GP VII LLC; OrbiMed Genesis GP LLC (director) bought $192k of stock
85. 2026-11-03 DGICA DONEGAL MUTUAL INSURANCE CO (ten_percent_owner) bought $140k of stock
86. 2026-11-03 HGV Potter Leonard (director) bought $104k of stock
87. 2026-11-03 AN Szlosek Thomas A (officer) bought $100k of stock
88. 2026-11-03 AN Szlosek Thomas A (officer) bought $100k of stock
89. 2026-11-03 JBLU Mittal Nik (director) bought $101k of stock
90. 2026-11-03 UPBD Karam Fahmi (director) bought $100k of stock
91. 2026-11-03 SPTX Torres Denice (director) bought $99k of stock
92. 2026-11-03 UPBD Wooters Rebecca (officer) bought $99k of stock
93. 2026-11-03 AN EDMUNDS C COLEMAN (officer) bought $55k of stock
94. 2026-11-02 INTC TAN LIP BU (director) bought $9.7M of stock
95. 2026-11-02 CRBG NIPPON LIFE INSURANCE CO (ten_percent_owner) bought $6.7M of stock
96. 2026-11-02 LRN Haggart Dylan G.; Fivespan Partners, LP; Fivespan Partners GP, LLC (director) bought $5.8M of stock
97. 2026-11-02 LRN Haggart Dylan G.; Fivespan Partners, LP; Fivespan Partners GP, LLC (director) bought $3.9M of stock
98. 2026-11-02 DOLE Pale Fire Capital SE; Pale Fire Capital SICAV a.s.; Pale Fire Capital investicni spolecnost a.s.; Senkypl Dusan; Barta Jan (ten_percent_owner) bought $3.1M of stock
99. 2026-11-02 BRK-B BERKSHIRE HATHAWAY INC; BUFFETT WARREN E (ten_percent_owner) bought $2.0M of stock
100. 2026-11-02 CACC TRYFOROS THOMAS N (director) bought $1.5M of stock